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Researchers could utilize a synthetic membrane infused with these two proteins to select which one particular it binds to. The affinity may be determined, or simply a competitive ligand binding assay may very well be performed to determine if there is any preference for a specific protein.
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As a result of chemical framework and relatedness to other SSRI’s, it is actually sensible to presume that MDAI would bind to either the serotonin receptor or the serotonin transporter protein.